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No differences were observed between treatments with respect to frequency, severity or outcome of AEs, or relationship to study product
The primary mechanisms of action include: Enhanced insulin secretion : GLP-1 receptor agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is released only when blood glucose levels are elevated, reducing hypoglycemia risk when used as monotherapy (though risk increases when combined with insulin or sulfonylureas)
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Research and anecdotal reports also suggest that Mounjaro tends to cause fewer and less pronounced side effects than Wegovy
Until that happens, retatrutide remains a research drug, not a routine treatment
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